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Opicapone in Early PD: Time to Revisit Off-Label COMT Use?

PHILADELPHIA — Early adjuvant use of opicapone (Ongentys) may reduce the risk for complications in patients with early Parkinson’s disease (PD) and no motor complications. The US Food and Drug Administration approved opicapone, a once-daily peripheral catechol-O-methyltransferase (COMT) inhibitor, in…

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